Researchers at the UC San Diego Stem Cell Program have used a rare disorder, Aicardi Goutieres (AGS), to explore fundamental brain mechanisms. By utilizing cortical organoids, or brains in a dish, they have tracked neurodevelopment while discovering new information about the relationship between retrotransposons and neuroinflammation. (Portuguese Translation) (#32916)

related programs

Genetics

1. 

   ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS
2. 

   Getting to the Heart of Cell Fate Control
3. 

   Engineering ‘Selfish’ Genes in Mice: Benefits and Risks - Exploring Ethics

Inflammation and Disease

1. 

   ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS
2. 

   Reconstrucción cerebral en laboratorio: surgimiento de la neuroinflamación de retrotransposones - Reconstructing the Brain in a Dish: Emergence of Neuroinflammation from Retrotransposons (Spanish Translation)
3. 

   The Appeal of Osteopathic Medicine with Hollis King, DO; Michael Kurisu, DO; and Paul J. Mills — UC Wellbeing Channel

Neurology

1. 

   Investigación sobre la Enfermedad de Alzheimer en la Comunidad Latina
2. 

   ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS
3. 

   What Role Do Genetics Play in Alzheimer’s? - On Our Mind

Neuroscience

1. 

   My Brain Made Me Buy It: The Neuroethics of Advertising - Exploring Ethics
2. 

   Investigación sobre la Enfermedad de Alzheimer en la Comunidad Latina
3. 

   Breathing Matters

Pediatrics / Family Medicine / Child Development

1. 

   Cranial Remolding Helmets
2. 

   Cerebral Palsy: A View From Both Sides
3. 

   A Team Approach to Care for Children with Cerebral Palsy

Regenerative Science

1. 

   Getting to the Heart of Cell Fate Control
2. 

   TBR1 and AUTS2: Sequential Regulators of Gene Expression in Cortical Development with Overlapping Neurodevelopmental Syndromes
3. 

   CARTA: Imagination and Human Origins: Alysson Muotri - Reconstructing the Neanderthal Mind in a Dish

Stem Cell Research

1. 

   ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS
2. 

   Getting to the Heart of Cell Fate Control
3. 

   TBR1 and AUTS2: Sequential Regulators of Gene Expression in Cortical Development with Overlapping Neurodevelopmental Syndromes