Dr. Michael Rabow, a palliative care physician, explores the wide-ranging side effects of androgen deprivation therapy (ADT) for prostate cancer and emphasizes strategies to reduce harm while improving quality of life. He outlines cardiovascular, hormonal, and emotional risks—including heart disease, osteoporosis, depression, and loss of vitality—and explains how early assessment and monitoring can help manage these effects. Dr. Rabow highlights evidence-based interventions such as physical activity and cognitive behavioral therapy (CBT), both of which improve symptoms like fatigue, sexual dysfunction, and emotional distress. He also reviews pharmacological options and stresses the importance of personalized, team-based care and shared decision-making over time. Recorded on 05/02/2025. (#40815)